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Analysis of the rate of force development reveals high neuromuscular fatigability in elderly patients with chronic kidney disease.

Antoine ChatrenetGiorgina PiccoliJean Michel AudebrandMassimo TorreggianiJulien BarbieuxCharly VaillantBaptiste MorelSylvain DurandBruno Beaune
Published in: Journal of cachexia, sarcopenia and muscle (2023)
Our study is the first to show that CKD patients have higher fatigability than controls, which may be associated with an impaired motor-unit recruitment, highlighting a neural drive disturbance with CKD. Further studies are needed to confirm these findings.
Keyphrases
  • chronic kidney disease
  • end stage renal disease
  • newly diagnosed
  • ejection fraction
  • prognostic factors
  • single molecule
  • middle aged
  • patient reported outcomes