Association of serum interferon-λ3 levels with hepatocarcinogenesis in chronic hepatitis C patients treated with direct-acting antiviral agents.

Emi Inoue-ShinomiyaMiyako MurakawaYasuhiro AsahinaMina NakagawaJun TsuchiyaAyako SatoTomoyuki TsunodaMasato MiyoshiSayuri NittaFukiko Kawai-KitahataYasuhiro ItsuiSeishin AzumaSei KakinumaKazumoto MurataMasashi MizokamiMamoru Watanabe

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2019)

Serum IFN-λ3 levels after HCV clearance are associated with the potential for HCC development. Interferon-λ3 could be helpful for elucidating the relationships among immunologic status, liver fibrosis, liver inflammation, and hepatocarcinogenesis, after achieving SVR.

Keyphrases

liver fibrosis
dendritic cells
hepatitis c virus
oxidative stress
human immunodeficiency virus
human health
hiv infected
antiretroviral therapy