Thymus atlanticus : A Source of Nutrients with Numerous Health Benefits and Important Therapeutic Potential for Age-Related Diseases.
Adil El MidaouiFarid KhalloukiRéjean CoutureFlorina MoldovanMahmoud Ali IsmaelBrice OngaliMarie Yvonne AkoumeChakib AlemAli Ait BoughrousWafa ZennouhiMhammed Chaoui RoqaiLhoussain HajjiImen GhzaielAnne VejuxGérard LizardPublished in: Nutrients (2023)
Thymus atlanticus (Lamiaceae) is a plant endemic to the Mediterranean basin that is found in significant quantities in the arid regions of Morocco. Thymus atlanticus is used in traditional medicine to treat infectious and non-infectious diseases. It is also used for the isolation of essential oils and for the seasoning of many dishes in the Mediterranean diet. The major constituents of Thymus atlanticus are saponins, flavonoids, tannins, alkaloids, various simple and hydroxycinnamic phenolic compounds, and terpene compounds. Several of these compounds act on signaling pathways of oxidative stress, inflammation, and blood sugar, which are parameters often dysregulated during aging. Due to its physiochemical characteristics and biological activities, Thymus atlanticus could be used for the prevention and/or treatment of age-related diseases. These different aspects are treated in the present review, and we focused on phytochemistry and major age-related diseases: dyslipidemia, cardiovascular diseases, and type 2 diabetes.
Keyphrases
- oxidative stress
- type diabetes
- infectious diseases
- cardiovascular disease
- healthcare
- signaling pathway
- public health
- mental health
- climate change
- heavy metals
- dna damage
- metabolic syndrome
- epithelial mesenchymal transition
- induced apoptosis
- pi k akt
- risk assessment
- ischemia reperfusion injury
- glycemic control
- cell proliferation
- newly diagnosed
- coronary artery disease
- combination therapy
- endoplasmic reticulum stress
- cell wall