Serum TNF-α Level as a Possible Predictor of Inhibitor Levels in Severe Hemophilia A.

Susi SusanahHarry RaspatiNur Melani Sari Lulu Eva Rakhmilla Yunia Sribudiani Octawyana Moestopo Puspasari Sinaga Ponpon S Idjradinata Ani Melani Maskoen

Published in: BioMed research international (2021)

The prevalence of FVIII inhibitor in severe PWHA in West Java, Indonesia, was 41.6%. The frequency of replacement therapy is a risk factor for inhibitor development. Serum TNF-α level might be used to differentiate between high and low inhibitor levels in severe hemophilia A, and this might support decision making regarding treatment options for inhibitor in severe hemophilia A.

Keyphrases

replacement therapy
early onset
rheumatoid arthritis