Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations.
Charles E BreezeEric HaugenAlex ReynoldsAndrew TeschendorffJenny van DongenQing LanNathaniel RothmanGuillaume BourqueIan DunhamStephan BeckJohn StamatoyannopoulosNora FranceschiniSonja I BerndtPublished in: Genome biology (2022)
In summary, we demonstrate that FORGE2 has the potential to uncover previously unreported disease-tissue associations and identify new candidate mechanisms. FORGE2 is a transparent, user-friendly web tool for the integrative analysis of loci discovered from GWAS.