IGF2 role in adrenocortical carcinoma biology.

Sofia S PereiraMariana P MonteiroMadalena M CostaÂngela MoreiraMarco G AlvesPedro F OliveiraIvana JarakDuarte Pignatelli

Published in: Endocrine (2019)

IGF2 is an excellent marker to differentiate ACC from ACAn. In addition, IGF2 was demonstrated to influence adrenocortical cancer cell proliferation, metabolism, and viability, but not the cell invasion. These data support that different IGF2 concentrations in ACC can be responsible for different biological behaviors of ACC.

Keyphrases

pi k akt
cell proliferation
binding protein
growth hormone
signaling pathway
papillary thyroid
cell cycle
squamous cell carcinoma
machine learning
squamous cell
young adults
artificial intelligence
lymph node metastasis
data analysis