Characterization of LP-Z Lipoprotein Particles and Quantification in Subjects with Liver Disease Using a Newly Developed NMR-Based Assay.

Shimpi Bedi Erwin GarciaElias J JeyarajahIrina ShalaurovaMaria Camila Perez-MatosZ Gordon JiangRobin P F DullaartSteven P MatyusWilliam J KirkJames D OtvosW Sean DavidsonMargery A Connelly

Published in: Journal of clinical medicine (2020)

LP-Z differ significantly in their lipid and protein content from LDL. Further studies are needed to fully understand the pathophysiological reason for the enhanced presence of LP-Z particles in patients with cholestasis and alcoholic liver disease.

Keyphrases

magnetic resonance
low density lipoprotein
liver injury
high resolution
drug induced
high throughput
protein protein
case control
amino acid
mass spectrometry
small molecule