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Cyanide-dependent control of terminal oxidase hybridization by Pseudomonas aeruginosa MpaR.

Marina K SmileyDoran C SekaranAlexa M Price-WhelanLars E P Dietrich
Published in: bioRxiv : the preprint server for biology (2023)
and elucidated the molecular details of this regulation. MpaR contains a DNA-binding domain and a domain predicted to bind pyridoxal phosphate (vitamin B6), a compound that is known to react spontaneously with cyanide. These observations provide insight into the understudied phenomenon of cyanide-dependent regulation of gene expression in bacteria.
Keyphrases
  • dna binding
  • gene expression
  • fluorescent probe
  • pseudomonas aeruginosa
  • transcription factor
  • dna methylation
  • single molecule
  • biofilm formation
  • acinetobacter baumannii
  • escherichia coli
  • drug resistant
  • label free