Cyanide-dependent control of terminal oxidase hybridization by Pseudomonas aeruginosa MpaR.
Marina K SmileyDoran C SekaranAlexa M Price-WhelanLars E P DietrichPublished in: bioRxiv : the preprint server for biology (2023)
and elucidated the molecular details of this regulation. MpaR contains a DNA-binding domain and a domain predicted to bind pyridoxal phosphate (vitamin B6), a compound that is known to react spontaneously with cyanide. These observations provide insight into the understudied phenomenon of cyanide-dependent regulation of gene expression in bacteria.