Divergent cyanoalkylation/cyanoalkylsulfonylation of enamides under organophotoredox catalytic conditions.
Durga GolaganiAbuthayir Mohamathu GhouseSriram AjmeeraSrirama Murthy AkondiPublished in: Organic & biomolecular chemistry (2022)
An organophotoredox-catalyzed divergent cyanoalkylation/cyanoalkylsulfonylation of enamides in a highly regio- and stereoselective manner has been reported. In this mild and efficient protocol, cyclobutanone oxime esters serve as a cyanoalkylating source and inexpensive K<sub>2</sub>S<sub>2</sub>O<sub>5</sub> serves as an SO<sub>2</sub> surrogate. Broad substrate scope, compatibility of various sensitive functional groups and further functional group transformation are the highlights of this method.
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