Significance of serological markers in the disease course of ulcerative colitis in a prospective clinical cohort of patients.
Gyorgy KovacsNora SipekiBoglarka SugaTamas TornaiKai FechnerGary L NormanZakera ShumsPeter Antal-SzalmasMária PappPublished in: PloS one (2018)
Even with low prevalence rates, present study gives further evidence to the role of certain antibodies as markers for distinct phenotype and disease outcome in UC. Considering the result of the multivariate analysis the novel antibodies investigated do not seem to be associated with poor clinical outcome in UC, only a classic antibody, IgA subtype ASCA remained an independent predictor of long-term immunosuppressive therapy.