Comparison of the Effects of Ezetimibe-Statin Combination Therapy on Major Adverse Cardiovascular Events in Patients with and without Diabetes: A Meta-Analysis.

Namki HongYong Ho LeeKenichi TsujitaJorge A GonzalezChristopher M KramerTomas KovarnikGeorge N KouvelosHiromichi SuzukiKyungdo HanChan Joo LeeSung Ha ParkByung Wan LeeBong Soo ChaEun Seok Kang

Published in: Endocrinology and metabolism (Seoul, Korea) (2018)

Ezetimibe-statin combination therapy was associated with greater cardiovascular benefits in patients with diabetes than in those without diabetes. Our findings suggest that ezetimibe-statin combination therapy might be a useful strategy in patients with diabetes at a residual risk of MACEs.

Keyphrases

combination therapy
cardiovascular disease
cardiovascular events
coronary artery disease
type diabetes
glycemic control
low density lipoprotein
emergency department
adipose tissue
weight loss
clinical evaluation