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Bioinspired Gram-Scale Synthesis of Alstoscholarinoid B.

Cheng LuoLing-Na ZhanYong Shi
Published in: Organic letters (2023)
Herein, we describe a gram-scale synthesis of alstoscholarinoid B, a rearranged triterpenoid with potent antihyperuricemic bioactivity. This synthesis was inspired by the biogenetic hypothesis and achieved in seven steps from oleanolic acid with an overall yield of 51%.
Keyphrases
  • gram negative
  • multidrug resistant
  • anti inflammatory