Exosomes from adipose-derived stem cells regulate M1/M2 macrophage phenotypic polarization to promote bone healing via miR-451a/MIF.

Rui LiDize LiHuanan WangKaiwen ChenSi WangJie XuPing Ji

Published in: Stem cell research & therapy (2022)

GNP-Exos can effectively regulate bone immune metabolism and further promote bone healing partly through immune regulation of miR-451a, which may provide a therapeutic direction for bone repair.

Keyphrases

bone mineral density
cell proliferation
soft tissue
long non coding rna
bone loss
bone regeneration
postmenopausal women
stem cells
body composition