Impact of GBA1 variants on long-term clinical progression and mortality in incident Parkinson's disease.

Thomas B StokerMarta CamachoSophie Winder-RhodesGanqiang LiuClemens R ScherzerThomas FoltynieJonathan EvansDavid P BreenRoger A BarkerCaroline H Williams-Gray

Published in: Journal of neurology, neurosurgery, and psychiatry (2020)

GBA1 variants, including those not associated with Gaucher disease, are common in PD and result in a more aggressive disease course.

Keyphrases

copy number
gene expression