Newly Recognized CNS Tumors in the 2021 World Health Organization Classification: Imaging Overview with Histopathologic and Genetic Correlation.

Ryan K Rigsby Pavan Brahmbhatt Amit Desai Girish Bathla Blake A Ebner Vivek Gupta Prasanna Vibhute Amit Kumar Agarwal

Published in: AJNR. American journal of neuroradiology (2023)

In 2021, the World Health Organization released an updated classification of CNS tumors. This update reflects the growing understanding of the importance of genetic alterations related to tumor pathogenesis, prognosis, and potential targeted treatments and introduces 22 newly recognized tumor types. Herein, we review these 22 newly recognized entities and emphasize their imaging appearance with correlation to histologic and genetic features.

Keyphrases

genome wide
high resolution
machine learning
deep learning
blood brain barrier
copy number
cancer therapy
gene expression
dna methylation
risk assessment
human health