Automated detection of immune effector cell-associated neurotoxicity syndrome via quantitative EEG.
Christine A EckhardtHaoqi SunPreeti MalikSyed QuadriMarcos Santana FirmeDaniel K JonesMeike van SleuwenAayushee JainZiwei FanJin JingWendong GeHusain H DanishCaron A JacobsonDaniel B RubinEyal Y KimchiSydney S CashMatthew J FrigaultJong Woo LeeJorg DietrichM Brandon WestoverPublished in: Annals of clinical and translational neurology (2023)
The EEG immune effector cell-associated neurotoxicity syndrome score possesses high criterion, construct, and predictive validity, which substantiates its use as a physiologic method to detect the presence and severity of neurotoxicity among patients undergoing chimeric antigen receptor T-cell therapy.