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Anti-tumor efficacy of an MMAE-conjugated antibody targeting cell surface TACE/ADAM17-cleaved Amphiregulin in breast cancer.

Kristopher A LofgrenSreeja SreekumarE Charles JenkinsKyle J ErnzenParaic A Kenny
Published in: Antibody therapeutics (2021)
This ADC targeting AREG has potential utility in the treatment of breast and other tumors in which proteolytic AREG shedding is a frequent event.
Keyphrases
  • cell surface
  • cancer therapy
  • photodynamic therapy
  • magnetic resonance
  • risk assessment
  • diffusion weighted
  • climate change
  • human health
  • diffusion weighted imaging
  • replacement therapy
  • smoking cessation