The Clinical Significance of Hepatic CD69+ CD103+ CD8+ Resident-Memory T Cells in Autoimmune Hepatitis.

Zhengrui YouYou LiQixia WangZhibin ZhaoYikang LiQiwei QianBo LiJun ZhangBingyuan HuangJubo LiangRuiling ChenZhuwan LyuYong ChenMin LianXiao XiaoQi MiaoJingyuan FangZhexiong LianM Eric GershwinRuqi TangXiong Ma

Published in: Hepatology (Baltimore, Md.) (2021)

Our data suggest that CD8+ TRM cells play a critical role in the pathogenesis of AIH, and GCs attenuate hepatic inflammation through direct inhibition of CD8+ TRM cell expansion.

Keyphrases

induced apoptosis
nk cells
oxidative stress
multiple sclerosis
single cell
working memory
patient safety
cell therapy
big data
mesenchymal stem cells
signaling pathway
machine learning
quality improvement
endoplasmic reticulum stress
drug induced