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An Improved qFibrosis Algorithm for Precise Screening and Enrollment into Non-Alcoholic Steatohepatitis (NASH) Clinical Trials.

Wei Qiang LeowPierre BedossaFeng LiuLai WeiKiat-Hon LimWei-Keat WanYayun RenPik-Eu Jason ChangChee-Kiat TanAileen WeeGeorge Boon-Bee Goh
Published in: Diagnostics (Basel, Switzerland) (2020)
The refined qFibrosis algorithm incorporated 26 novel parameters that showed a good discriminatory ability for NASH fibrosis stage 1 and 2 cases, representing an invaluable assistive tool for in-house pathologists when screening patients for NASH clinical trials.
Keyphrases
  • clinical trial
  • end stage renal disease
  • machine learning
  • deep learning
  • newly diagnosed
  • ejection fraction
  • chronic kidney disease
  • peritoneal dialysis
  • prognostic factors
  • healthcare
  • open label
  • liver fibrosis
  • phase iii