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Antimicrobial endotoxin-neutralizing peptides promote keratinocyte migration via P2X7 receptor activation and accelerate wound healing in vivo.

Anja PfalzgraffSergio Bárcena-VarelaLena HeinbockelThomas GutsmannKlaus BrandenburgGuillermo Martinez-de-TejadaGünther Weindl
Published in: British journal of pharmacology (2018)
Our data suggest the potential application of Pep19-2.5 in the treatment of non-infected and S. aureus-infected wounds and provide insights into the mechanism involved in Pep19-2.5-induced wound healing.
Keyphrases
  • wound healing
  • high glucose
  • staphylococcus aureus
  • diabetic rats
  • big data
  • dengue virus
  • combination therapy
  • human health
  • risk assessment
  • machine learning
  • amino acid
  • zika virus
  • aedes aegypti