Microbiota- and Radiotherapy-Induced Gastrointestinal Side-Effects (MARS) Study: A Large Pilot Study of the Microbiome in Acute and Late-Radiation Enteropathy.
Miguel Reis FerreiraH Jervoise N AndreyevKabir MohammedLesley TrueloveSharon M GowanJia LiSarah L GullifordJulian R MarchesiDavid P DearnaleyPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
The microbiota presents opportunities to predict, prevent, or treat radiation enteropathy. We report the largest clinical study to date into associations of the microbiota with acute and late radiation enteropathy. An altered microbiota associates with early and late radiation enteropathy, with clinical implications for risk assessment, prevention, and treatment of radiation-induced side-effects.See related commentary by Lam et al., p. 6280.