Circulating biomarkers of left ventricular hypertrophy in pediatric coarctation of the aorta.
Benjamin S FrankTracy T UrbanKarlise LewisSuhong TongCourtney CassidyMax B MitchellChristopher S NicholsJesse A DavidsonPublished in: Congenital heart disease (2019)
Persistent left ventricular hypertrophy and abnormal relative wall thickness at intermediate-term follow-up was rare compared to previous studies. A model combining pre-op endothelin 1 and ST2 level demonstrated reasonable accuracy at predicting persistent abnormalities in this cohort. Larger studies will be needed to validate this finding and further explore the mechanism of persistent left ventricular remodeling in this population.
Keyphrases
- left ventricular
- hypertrophic cardiomyopathy
- heart failure
- cardiac resynchronization therapy
- aortic stenosis
- acute myocardial infarction
- mitral valve
- left atrial
- case control
- aortic valve
- preterm infants
- pulmonary artery
- coronary artery
- atrial fibrillation
- percutaneous coronary intervention
- ejection fraction
- gestational age