Optimizing β-lactam-containing antibiotic combination therapy for the treatment of Buruli ulcer.

Salvatore D'AgatePeter VelickovicNoelia García-Barrios Santiago Ramón-García Oscar Della Pasqua

Published in: British journal of clinical pharmacology (2024)

The higher PTA values support the proposed 4-drug combination (rifampicin, clarithromycin, AMX/CLV) currently under clinical investigation. Our findings also suggest that higher rifampicin doses might contribute to enhanced treatment efficacy.

Keyphrases

combination therapy
mycobacterium tuberculosis
helicobacter pylori
emergency department
pulmonary tuberculosis
gram negative