Prognostic significance of an invasive leader cell-derived mutation cluster on chromosome 16q.

Brian PedroManali RupjiBhakti DwivediJeanne KowalskiJessica M KonenTaofeek K OwonikokoSuresh R RamalingamPaula M VertinoAdam I Marcus

Published in: Cancer (2020)

This represents the first leader cell mutation signature identified in patients and has the potential to better stratify high-risk NSCLC and ultimately improve patient outcomes.

Keyphrases

end stage renal disease
ejection fraction
small cell lung cancer
newly diagnosed
single cell
prognostic factors
gene expression
dna methylation
risk assessment
mesenchymal stem cells
tyrosine kinase