Real time PCR detection of common CYP2D6 genetic variants and its application in a Karen population study.

Kanokpich PuaprasertCindy ChuNaowarat SaralambaNicholas P J DayFrancois NostenNicholas J WhiteArjen M DondorpMallika Imwong

Published in: Malaria journal (2018)

The newly developed ASO assay is a reliable and rapid tool for large-scale CYP2D6 genotyping. The high frequency of the CYP2D6*10 allele in the Karen population warrants further assessment of its association with the radical curative efficacy of primaquine.

Keyphrases

real time pcr
high frequency
transcranial magnetic stimulation
high throughput
loop mediated isothermal amplification
rectal cancer
quantum dots
clinical evaluation