Integrating spatial transcriptomics and single-cell RNA-sequencing reveals the alterations in epithelial cells during nodular formation in benign prostatic hyperplasia.

Xiawei FeiJican LiuJunyan XuHongyan JingZhonglin CaiJiasheng YanZhenqi WuHuifeng LiZhong WangYan-Ting Shen

Published in: Journal of translational medicine (2024)

This study elucidated the comprehensive landscape of epithelial cells during in vivo nodular formation in patients, thereby offering novel insights into the initiation and progression of BPH.

Keyphrases

single cell
benign prostatic hyperplasia
lower urinary tract symptoms
rna seq
end stage renal disease
high throughput
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
patient reported outcomes