Activation of MAT2A-RIP1 signaling axis reprograms monocytes in gastric cancer.

Yan ZhangHui YangJun ZhaoPing WanYe HuKun LvYiRen HuXi YangMing-Zhe Ma

Published in: Journal for immunotherapy of cancer (2021)

Our data cast light on a novel mechanism by which methionine metabolism regulates the anti-inflammatory functions of monocytes in GC. MAT2A might be a potential therapeutic target for cancer cells as well as TAMs in GC.

Keyphrases

anti inflammatory
dendritic cells
peripheral blood
gas chromatography
electronic health record
big data
mass spectrometry
immune response
amino acid
machine learning
risk assessment
artificial intelligence
deep learning
data analysis
liquid chromatography