Prognostic Biomarkers of Sarcoidosis: A Comparative Study of Serum Chitotriosidase, ACE, Lysozyme, and KL-6.

Laura BergantiniFrancesco BianchiPaolo CameliMaria Antonietta MazzeiAnnalisa FuiPiersante SestiniPaola RottoliElena Bargagli

Published in: Disease markers (2019)

KL-6 is a reliable biomarker of fibrotic lung involvement in sarcoidosis patients. Among biomarkers, KL-6 showed the best sensitivity and serum chitotriosidase the best specificity, even in patients on chronic steroid therapy, and seemed to correlate with extrapulmonary localizations.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
angiotensin ii
mesenchymal stem cells
systemic sclerosis
idiopathic pulmonary fibrosis
patient reported