Intestinal Bacterial Translocation Contributes to Diabetic Kidney Disease.
Hoang Thuy LinhYasunori IwataYasuko SendaYukiko Sakai-TakemoriYusuke NakadeMegumi OshimaShiori Nakagawa-YonedaHisayuki OguraKoichi SatoTaichiro MinamiShinji KitajimaTadashi ToyamaYuta YamamuraTaro MiyagawaAkinori HaraMiho ShimizuKengo FuruichiNorihiko SakaiHiroyuki YamadaKatsuhiko AsanumaKouji MatsushimaTakashi WadaPublished in: Journal of the American Society of Nephrology : JASN (2022)
Impaired MAVS signaling both in the kidney and intestine contributes to the disrupted homeostasis, leading to diabetic kidney disease progression. Controlling intestinal homeostasis may offer a novel therapeutic approach for this condition.