HIV-1C in-House RNA-Based Genotyping Assay for Detection of Drug Resistance Mutations in Samples with Low-Level Viral Loads.
Ontlametse T BarengWonderful T ChogaSegomotso T MaphorisaSekgabo SeselamarumoKaelo K SeatlaPatrick T MokgethiDorcas MaruapulaMompati L MogweleDoreen DitshwaneloNatasha O MorakaIrene GobeModisa S MotswalediJoseph M MakhemaRosemary MusondaRoger ShapiroMax EssexVlad NovitskySikhulile MoyoSimani GaseitsiwePublished in: Infection and drug resistance (2022)
The in-house HIV genotyping assay successfully genotyped 72% of LLV samples and was able to detect 17% of DRM amongst them. Our results highlight the possibility and clinical significance of genotyping HIV among individuals with LLV.