Prognostic impact of combined immunoprofiles in oropharyngeal squamous cell carcinoma patients with respect to AJCC 8th edition.

Dominik GurinMarek SlavikMarketa HermanovaTetiana ShatokhinaJiri SanaTomas KazdaIveta SelingerovaParwez AhmadPavel SmilekZuzana HorakovaMichal HendrychPavel SlampaOndrej Slaby

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2018)

Combined immunoprofiles of p16, EGFR, and CD44 might provide valuable prognostic and predictive information for the individual OPSCC patients, especially in terms of response to IMRT and prediction of treatment outcomes. Application of the AJCC 8th edition staging for HPV+ OPSCC proved to improve hazard discrimination and prognostication of OPSCC.

Keyphrases

squamous cell carcinoma
end stage renal disease
small cell lung cancer
newly diagnosed
ejection fraction
prognostic factors
lymph node
healthcare
tyrosine kinase
radiation therapy
lymph node metastasis