Genome-Wide Analysis of Left Ventricular Maximum Wall Thickness in the UK Biobank Cohort Reveals a Shared Genetic Background With Hypertrophic Cardiomyopathy.

Nay Aung Luis Rocha LopesStefan van DuijvenbodenAndrew R Harper Anuj GoelChristopher GraceCarolyn Y Ho William S Weintraub Christopher M Kramer Stefan Neubauer Hugh C Watkins Steffen Erhard Petersen Patricia B Munroe

Published in: Circulation. Genomic and precision medicine (2023)

Our findings provide novel insights into the genetic underpinning of LVMWT and highlight its shared genetic background with HCM, supporting future endeavours to elucidate the genetic etiology of HCM.

Keyphrases

hypertrophic cardiomyopathy
left ventricular
genome wide
heart failure
genome wide analysis
acute myocardial infarction
cardiac resynchronization therapy
aortic stenosis
optical coherence tomography
current status
acute coronary syndrome
transcatheter aortic valve replacement