Login / Signup

Neoadjuvant Chemotherapy for Intrahepatic, Perihilar, and Distal Cholangiocarcinoma: a National Population-Based Comparative Cohort Study.

Alessandro ParenteSivesh Kathir KamarajahMarco BaiaFabio TirottaTommaso M ManziaMohammed Abu HilalTimothy M PawlikSteven A WhiteFadi S Dahdaleh
Published in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2023)
This study associated NAC with increased OS for all CCA subtypes, even in patients with margin-negative and node-negative disease; however, no differences were found between NAC and AC. Our results highlight that a careful and interdisciplinary evaluation should be sought to consider NAC in CCA and warrant the need of larger studies to provide robust recommendation.
Keyphrases
  • neoadjuvant chemotherapy
  • transcription factor
  • lymph node
  • locally advanced
  • sentinel lymph node
  • genome wide analysis
  • minimally invasive
  • quality improvement
  • squamous cell carcinoma
  • radiation therapy