Optimal Timing for Resumption of Anticoagulation After Intracranial Hemorrhage in Patients With Mechanical Heart Valves.

Megan E Barra Rachel FormanBianca Long-FazioAlexander E Merkler Mahmut Edip Gurol Saef Izzy Richa Sharma

Published in: Journal of the American Heart Association (2024)

In this study of patients with ICH and mechanical heart valves, there was no difference in 30-day thrombotic and hemorrhagic brain-related outcomes when anticoagulation was resumed within 7 versus 7 to 30 days after ICH. Withholding anticoagulation >30 days was associated with severe baseline ICH, higher in-hospital case fatality, and elevated AIS risk.

Keyphrases

atrial fibrillation
venous thromboembolism
aortic valve
heart failure
aortic valve replacement
healthcare
resting state
early onset
white matter
emergency department
functional connectivity
transcatheter aortic valve replacement
adverse drug
left ventricular
weight loss