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Silencing of circCRIM1 Drives IGF2BP1-Mediated NSCLC Immune Evasion.

Wenbei PengLinlin YeQianqian XueXiaoshan WeiZihao WangXuan XiangSiyu ZhangPei ZhangHaolei WangQiong Zhou
Published in: Cells (2023)
This study identifies circCRIM1 as a new tumor suppressor that inhibits tumor immune evasion through a competitive combination with IGF2BP1 to destabilize HLA-F mRNA.
Keyphrases
  • binding protein
  • small cell lung cancer
  • pi k akt
  • genome wide
  • growth hormone
  • advanced non small cell lung cancer
  • gene expression
  • epidermal growth factor receptor