A povarov-type reaction to access tetrahydroquinolines from N -benzylhydroxylamines and alkenes in HFIP.

Here, we report the synthesis of tetrahydroquinolines between newly developed N -benzylhydroxylamine reagents and alkenes using HFIP as a solvent. This transformation is notably applicable to highly electronically deactivated styrenes and aliphatic alkenes, expanding the range of tetrahydroquinolines attainable.