Role of altered IL-33/ST2 immune axis in the immunobiology of Guillain-Barré syndrome.
Praveen P SharmaDoniparthi V SeshagiriMadhu NagappaThrinath MullapudiNikhitha SreenivasSaikat DeySumanth ShivaramRahul WahatuleVijay KumawatBinu V Sreekumaran NairSriganesh KamathSanjib SinhaArun B TalyMonojit DebnathPublished in: European journal of neurology (2022)
The IL-33/ST2 axis is suggested to influence the immunopathogenesis of GBS. Genetic variants of Il1rl1 gene might serve as a risk determinant of GBS and plasma sST2 levels might emerge as a biomarker of severity of GBS, if replicated further by other studies.