Elevated serum interleukin-2 after gluten correlates with symptoms and is a potential diagnostic biomarker for coeliac disease.

Jason A Tye-DinA James M DavesonHooi C EeGautam GoelJames MacDougallSarah AcasterKaela E GoldsteinJohn L DzurisKristin M NeffKenneth E Truitt Robert P Anderson

Published in: Alimentary pharmacology & therapeutics (2019)

Serum interleukin-2 elevations correlate with timing and severity of symptoms after gluten in coeliac disease. Standardised bolus gluten food challenge and interleukin-2 assessment could provide a valuable clinical test to monitor and diagnose coeliac disease in patients established on a gluten-free diet.

Keyphrases

celiac disease
end stage renal disease
ejection fraction
irritable bowel syndrome
chronic kidney disease
newly diagnosed
prognostic factors
physical activity
sleep quality
peritoneal dialysis
patient reported outcomes