C(5) Site-Selective Functionalization of (S)-Cotinine.

Published in: The Journal of organic chemistry (2017)

(S)-(-)-Cotinine 2 undergoes direct and site-selective iridium-catalyzed borylation to provide boronate ester 3 and bromide 4 which offer flexible entry to a range of C(5)-substituted cotinine variants.

Keyphrases

copy number
molecular docking
room temperature
gene expression
dna methylation
genome wide