Chronic Critical Illness Patients Fail to Respond to Current Evidence-Based Intensive Care Nutrition Secondarily to Persistent Inflammation, Immunosuppression, and Catabolic Syndrome.
Martin D RosenthalTrina BalaZhongkai WangTyler LoftusFrederick MoorePublished in: JPEN. Journal of parenteral and enteral nutrition (2020)
Despite early, adequate, evidence-based ICU nutrition, septic surgical ICU patients who develop CCI exhibit persistent inflammation, immunosuppression, and catabolism with unacceptable long-term morbidity and mortality. Although current evidence-based ICU nutrition may improve short-term ICU outcomes, novel adjuncts are needed to improve long-term outcomes for CCI patients.
Keyphrases
- intensive care unit
- end stage renal disease
- ejection fraction
- physical activity
- chronic kidney disease
- newly diagnosed
- oxidative stress
- mechanical ventilation
- prognostic factors
- neuropathic pain
- acute kidney injury
- patient reported outcomes
- spinal cord injury
- spinal cord
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation