Association between systemic leptin and neurotensin concentration in adult individuals with and without type 2 diabetes mellitus.

I BarchettaG CiccarelliF A CiminiV CeccarelliM Orho-MelanderO MelanderMaria Gisella Cavallo

Published in: Journal of endocrinological investigation (2018)

Circulating leptin is associated with higher proNT levels independent of diabetes, obesity and metabolic syndrome components; besides its effects on central leptin signaling, NT may influence energy balance by modulating circulating leptin concentration likely through a mechanism involving gut fat absorption.

Keyphrases

metabolic syndrome
type diabetes
insulin resistance
glycemic control
cardiovascular disease
adipose tissue
cardiovascular risk factors
signaling pathway
skeletal muscle