Clinical-pathological features in placentas of pregnancies with SARS-CoV-2 infection and adverse outcome: case series with and without congenital transmission.

Mehreen ZaighamDavid GisselssonAnna SandAnna-Karin WikströmEmma von WowernDavid A SchwartzLinda IorizzoMaria NelanderMarie BlombergNikos PapadogiannakisSandra HolmströmÅsa LeijonhfvudVerena Sengpiel

Published in: BJOG : an international journal of obstetrics and gynaecology (2022)

SARS-CoV-2 can cause rapid placental dysfunction with subsequent acute fetal hypoxia leading to intrauterine fetal compromise. Associated placental pathology included massive perivillous fibrinoid deposition, intervillositis and trophoblast degeneration.

Keyphrases

sars cov
respiratory syndrome coronavirus
liver failure
respiratory failure
preterm birth
endothelial cells
drug induced
gestational age
emergency department
pregnancy outcomes
loop mediated isothermal amplification
quantum dots
extracorporeal membrane oxygenation
sensitive detection