Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity.

Maxime M BosRaymond NoordamKate BennettMarian BeekmanDennis O Mook-KanamoriKo Willems van DijkP Eline SlagboomTorbjörn LundstedtIzabella SurowiecDiana van Heemst

Published in: Metabolomics : Official journal of the Metabolomic Society (2020)

We found several plasma metabolites that are associated with early disturbances in glucose metabolism and insulin sensitivity of which five were also higher in individuals with diabetes mellitus.

Keyphrases

middle aged
ms ms
mass spectrometry
genome wide
blood glucose
blood pressure
metabolic syndrome
adipose tissue
dna methylation
glycemic control