Effects of Tirzepatide vs Semaglutide on β-cell Function, Insulin Sensitivity, and Glucose Control During a Meal Test.

Kieren J Mather Andrea MariTim HeiseJ Hans DeVriesMing HuaShweta UrvaTamer CoskunAxel HauptRobert J HeineEdward PrattMelissa K ThomasZvonko Milicevic

Published in: The Journal of clinical endocrinology and metabolism (2024)

These results suggest that the greater glycemic control observed for tirzepatide manifests as improved fasting glucose and glucose excursion control, due to improvements in ISR, insulin sensitivity, and glucagon suppression.

Keyphrases

blood glucose
glycemic control
type diabetes
weight loss
metabolic syndrome
adipose tissue