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Diagnostic and Dosimetry Features of [ 64 Cu]CuCl 2 in High-Grade Paediatric Infiltrative Gliomas.

Francesco FizGianluca BottoniMartina UgoliniSergio RighiAlessio CironeMaria Carmen GarganeseAntonio VerricoAndrea RossiClaudia MilanaccioAntonia RamagliaAngela MastronuzziMassimo Eraldo AbateAntonella CacchioneCarlo GandolfoGiovanna Stefania ColafatiMaria Luisa GarrèGiovanni MoranaArnoldo Piccardo
Published in: Molecular imaging and biology (2022)
is a well-tolerated radiotracer with reasonably favourable dosimetric properties, showing selective uptake in tumour areas with visible contrast enhancement and necrosis, thus suggesting that blood-brain barrier damage is a pre-requisite for its distribution to the intracranial structures. Moreover, tracer uptake showed an accumulating trend over time. These characteristics could deserve further analysis, to determine whether this radiopharmaceutical might have a possible therapeutic role as well.
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