Reference ranges of anti-Müllerian hormone and interaction with placental biomarkers in early pregnancy: the Generation R Study, a population-based prospective cohort study.

Ramon Henny Maria DykgraafS Schalekamp-TimmermansM C AdankS A A van den BergB M N van de Lang-BornT I M KorevaarA KumarB KalraG V SavjaniE A P SteegersY V LouwersJ S E Laven

Published in: Endocrine connections (2023)

In this large study, we show that AMH levels in early pregnancy decrease with advancing gestational age. The association between AMH and the placental biomarkers hCG, sFLT, and PLGF suggests a better placental development with lower vascular resistance in mothers with higher AMH levels. Hence, AMH might be useful in predicting adverse pregnancy outcomes due to impaired placental development.

Keyphrases

gestational age
pregnancy outcomes
preterm birth
pregnant women
birth weight
emergency department
body mass index