Steroid therapy in acute exacerbation of fibrotic interstitial lung disease.
Kavya KoshyHayley BarnesErica FarrandIan N GlaspolePublished in: Respirology (Carlton, Vic.) (2024)
In this two-centre retrospective study of 107 patients, AE-FILD demonstrates a high risk of mortality, at a level similar to that seen for AE-IPF, despite steroid treatment. Clinicians should consider other precipitating factors for exacerbations and use steroids judiciously. Further prospective trials are needed to determine the role of corticosteroids in AE-FILD.
Keyphrases
- interstitial lung disease
- idiopathic pulmonary fibrosis
- systemic sclerosis
- chronic obstructive pulmonary disease
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- liver failure
- cystic fibrosis
- palliative care
- respiratory failure
- prognostic factors
- peritoneal dialysis
- cardiovascular events
- stem cells
- cardiovascular disease
- risk factors
- coronary artery disease
- replacement therapy