Causal Relationships Between Circulating Inflammatory Proteins and Obstructive Sleep Apnea: A Bidirectional Mendelian Randomization Study.

Zhengjie ChenJinjie ZengXiang PeiJingjing ZhaoFang ZhaoGuoxin ZhangKexin LiangJiarong LiXiaoyun Zhao

Published in: Nature and science of sleep (2024)

Through this bidirectional MR study, we have identified 12 upstream regulatory proteins and 5 downstream effect proteins that are linked to OSA. These findings hold promise in providing potential therapeutic targets for the inflammatory mechanisms underlying OSA.

Keyphrases

obstructive sleep apnea
positive airway pressure
oxidative stress
computed tomography
machine learning
big data
sleep apnea
climate change