MyD88 exacerbates inflammation-induced bone loss by modulating dynamic equilibrium between Th17/Treg cells and subgingival microbiota dysbiosis.

Po-Yan HsiaoRen-Yeong HuangLin-Wei HuangChing-Liang ChuThomas Van DykeLian-Ping MauChia-Dan ChengCheng-En SungPei-Wei WengYu-Chiao WuYi-Shing ShiehWan-Chien Cheng

Published in: Journal of periodontology (2024)

MyD88 plays an important role in inflammation-induced bone loss by modulating the dynamic equilibrium between Th17/Treg cells and dysbiosis in P. gingivalis-induced experimental periodontitis.

Keyphrases

bone loss
induced apoptosis
diabetic rats
high glucose
oxidative stress
cell cycle arrest
signaling pathway
drug induced
toll like receptor
molecular dynamics
endothelial cells
inflammatory response