Metabolomic Links between Sugar-Sweetened Beverage Intake and Obesity.

Bingjie ZhouReiko IchikawaLaurence D ParnellSabrina E NoelXiyuan ZhangShilpa N BhupathirajuCaren E SmithKatherine L TuckerJosé Marìa Ordovàs Chao-Qiang Lai

Published in: Journal of obesity (2020)

We identified two key metabolic pathways that link SSB intake to obesity, revealing the potential of phosphatidylcholine and lysophospholipid to modulate how SSB intake can increase obesity risk. The interaction between genetic variants related to these pathways and SSB intake on obesity further supports the mechanism.

Keyphrases

weight gain
insulin resistance
metabolic syndrome
weight loss
type diabetes
high fat diet induced
body mass index
skeletal muscle